Association of Nadir PSA >0.5ng/Ml after Dose Escalated External Beam Radiation With Prostate Cancer-Specific Endpoints
نویسندگان
چکیده
منابع مشابه
Predictors of castration-resistant prostate cancer after dose-escalated external beam radiotherapy.
BACKGROUND Castration-resistant prostate cancer (CRPC) is a near uniformly fatal form of prostate cancer; however, information on time to development and predictors for progression to CRPC is limited. We report a detailed longitudinal study for development of CRPC in men initially treated with external beam radiotherapy (EBRT). METHODS During 1991-2008, 2,478 patients with clinically localize...
متن کاملSalvage low-dose-rate 125I partial prostate brachytherapy after dose-escalated external beam radiotherapy
PURPOSE To report outcomes on 5 patients treated with salvage partial low-dose-rate (LDR) 125-iodine ((125)I) permanent prostate seed brachytherapy (BT) for biopsy-proven locally persistent prostate cancer, following failure of dose-escalated external beam radiotherapy (EBRT). MATERIAL AND METHODS A retrospective review of the Fox Chase Cancer Center prostate cancer database identified five p...
متن کاملThe Current Role of Androgen Deprivation in Patients Undergoing Dose-Escalated External Beam Radiation Therapy for Clinically Localized Prostate Cancer
Purpose. To review existing literature on the role of androgen deprivation therapy (ADT) with dose escalated radiation therapy. Methods and Materials. A PubMed search was undertaken to identify relevant articles. Results. Multiple recent studies were identified examining the role of ADT in the current era of radiation dose-escalation. Among the reviewed studies, varying radiation doses and tech...
متن کاملInterval to biochemical failure as a biomarker for cause-specific and overall survival after dose-escalated external beam radiation therapy for prostate cancer.
BACKGROUND After external beam radiation therapy (EBRT) for prostate cancer, a short interval to biochemical failure of <18 months has been proposed as a surrogate for cause-specific survival. Because EBRT dose influences biochemical failure, the authors investigated the interval to biochemical failure in a cohort of patients treated with dose-escalated EBRT. METHODS From 1998 to 2008, 710 pa...
متن کاملPSA after radiation for prostate cancer.
The introduction of prostate-specific antigen (PSA) as a reliable tumor marker for prostate cancer brought significant changes in the end points used for outcome reporting after therapy. With regard to a definition of failure after radiation, a consensus was reached in 1996 that took into account the particular issues of an intact prostate after therapy. Over the next several years, the consens...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2017
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2017.06.1235